Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA5A | P35218 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560999 | 0.85 | HTT (0.41) | MAPTHTTKDM4EMITFNPY1R | |
| SCHEMBL11630762 | 0.79 | MAPT (0.38) | MAPTHTTKDM4EMITFNPY1R | |
| SCHEMBL8601738 | 0.77 | ALDH1A1 (0.42) | MAPTHTTKDM4EMITFNPY1R | |
| SCHEMBL11713155 | 0.77 | MAPT (0.45) | MAPTHTTKDM4EMITFNPY1R | |
| SCHEMBL8565505 | 0.77 | MAPT (0.45) | MAPTHTTKDM4EMITFNOD2 | |
| SCHEMBL8566342 | 0.76 | ALDH1A1 (0.48) | MAPTHTTKDM4EMITFNPY1R | |
| SCHEMBL8565961 | 0.76 | CA2 (0.39) | MAPTHTTNPY1RCA2CA1 | |
| SCHEMBL3688848 | 0.76 | MAPT (0.47) | MAPTHTTKDM4EMITFNPY1R | |
| SCHEMBL8600998 | 0.75 | TXNRD1 (0.43) | MAPTHTTKDM4EMITFNPY1R | |
| SCHEMBL8625607 | 0.75 | CA12 (0.35) | MAPTHTTKDM4EMITFNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |