Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PLG | P00747 | 3/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601792 | 1.00 | LMNA (0.50) | LMNAPLGPLATNAAACHRNB2 | |
| Hydrochloric Acid SCHEMBL3792018 | 0.98 | LMNA (0.48) | LMNAPLGPLATNAAACHRNB2 | |
| SCHEMBL8594845 | 0.91 | NAAA (0.58) | LMNAPLGPLATNAAAGNAI3 | |
| SCHEMBL8594847 | 0.91 | NAAA (0.58) | LMNAPLGPLATNAAAGNAI3 | |
| Hydrochloric Acid SCHEMBL8599841 | 0.90 | NAAA (0.57) | LMNAPLGPLATNAAAGNAI3 | |
| Hydrochloric Acid SCHEMBL8599842 | 0.90 | NAAA (0.57) | LMNAPLGPLATNAAAGNAI3 | |
| SCHEMBL8628590 | 0.87 | NAAA (0.67) | LMNAPLGNAAAGNAI3GNAO1 | |
| SCHEMBL8598693 | 0.87 | NAAA (0.67) | LMNAPLGNAAAGNAI3GNAO1 | |
| SCHEMBL8598695 | 0.87 | NAAA (0.67) | LMNAPLGNAAAGNAI3GNAO1 | |
| SCHEMBL8628588 | 0.87 | NAAA (0.67) | LMNAPLGNAAAGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9713649-B2 | PSMA-targeting imaging agents | THE CLEVELAND CLINIC FOUNDATION (US) | 2017-07-25 | — | — | US | disclosed |
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |