Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | ODC1 | P11926 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349825 | 0.80 | GLRA1 (0.38) | SMN1; SMN2HIF1AARG1ARG2ODC1 | |
| SCHEMBL825611 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2HIF1AARG1ARG2ODC1 | |
| SCHEMBL619053 | 0.76 | TSHR (0.35) | SMN1; SMN2HIF1AARG1ARG2 | |
| SCHEMBL2007928 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2HIF1AARG1ARG2ODC1 | |
| SCHEMBL19322605 | 0.74 | FDPS (0.39) | ARG1ARG2MAPT | |
| SCHEMBL8991294 | 0.73 | SMN1; SMN2 (0.32) | SMN1; SMN2HIF1ABLMPMP22 | |
| SCHEMBL6890454 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL5960916 | 0.73 | FAAH (0.48) | — | |
| SCHEMBL681314 | 0.72 | SMN1; SMN2 (0.38) | SMN1; SMN2HIF1AARG1ARG2ODC1 | |
| SCHEMBL19066818 | 0.71 | FAAH (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820313-A2 | RADIOLABELED PEPTIDES FOR DIAGNOSIS AND THERAPY | Diatide, Inc. (US) | 1998-01-28 | — | — | EP | disclosed |
| EP-0804252-A2 | MONOAMINE, DIAMIDE, THIOL-CONTAINING METAL CHELATING AGENTS | DIATECH, INC. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996030055-A2 | RADIOLABELED PEPTIDES FOR DIAGNOSIS AND THERAPY | DIATIDE, INC. (US) | 1996-10-03 | — | — | WO | disclosed |
| WO-1995033497-A1 | MONOAMINE, DIAMIDE, THIOL-CONTAINING METAL CHELATING AGENTS | DIATECH, INC. (US) | 1995-12-14 | — | — | WO | disclosed |
| US-5322929-A | Tri- and tetrapeptides as ligands | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1994-06-21 | — | — | US | disclosed |
| US-4980147-A | INJECTING AS IMAGING AGENTS IN SCINTIGRAPHIC UROGRAPHY | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0173424-A1 | Radiolabeled technetium chelates for use in renal function determinations | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1986-03-05 | — | — | EP | disclosed |