Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | ARG2 | P78540 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ODC1 | P11926 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GGT1 | P19440 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681314 | 0.85 | SMN1; SMN2 (0.38) | SMN1; SMN2HIF1AGLRA1SLC6A9OR51E2 | |
| SCHEMBL349825 | 0.83 | GLRA1 (0.38) | SMN1; SMN2HIF1AGLRA1SLC6A9OR51E2 | |
| SCHEMBL1005537 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2HIF1AGLRA1SLC6A9OR51E2 | |
| SCHEMBL2007928 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2HIF1AARG1ARG2KDM4E | |
| SCHEMBL619053 | 0.79 | TSHR (0.35) | SMN1; SMN2HIF1AARG1ARG2TSHR | |
| SCHEMBL8601948 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2HIF1AARG1ARG2KDM4E | |
| SCHEMBL7366566 | 0.77 | SMN1; SMN2 (0.33) | SMN1; SMN2HIF1AKDM4ELMNA | |
| SCHEMBL8991294 | 0.75 | SMN1; SMN2 (0.32) | SMN1; SMN2HIF1ABLMPMP22KMT2A | |
| SCHEMBL11849715 | 0.75 | ODC1 (0.43) | SMN1; SMN2HIF1AGLRA1SLC6A9OR51E2 | |
| SCHEMBL6009380 | 0.74 | ALOX15 (0.39) | SMN1; SMN2KDM4ELMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116083531-A | Sc3T-seq method for accurately analyzing single-cell APA site | 上海交通大学 | 2023-05-09 | — | — | CN | disclosed |
| EP-2582715-B1 | GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2018-11-28 | — | — | EP | disclosed |
| US-9315546-B2 | Growth hormone secretatogue receptor antagonists and uses thereof | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2016-04-19 | — | — | US | disclosed |
| US-20130172242-A1 | GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF | MCGILL UNIVERSITY (CA) | 2013-07-04 | — | — | US | disclosed |
| EP-2582715-A2 | GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF | The Administrators of the Tulane Educational Fund (US) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011159917-A2 | GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2011-12-22 | — | — | WO | disclosed |
| EP-0562040-B1 | ARYL MONOSULFONATE COLLECTORS USEFUL IN THE FLOTATION OF MINERALS | DOW CHEMICAL CO (US) | 1997-07-23 | — | — | EP | disclosed |
| WO-1995003891-A1 | ARYL ETHER MONOSULFONATE COLLECTORS USEFUL IN THE FLOTATION OF MINERALS | THE DOW CHEMICAL COMPANY (US) | 1995-02-09 | — | — | WO | disclosed |
| EP-0562040-A4 | — | — | 1994-02-09 | — | — | EP | disclosed |
| EP-0562040-A1 | ARYL MONOSULFONATE COLLECTORS USEFUL IN THE FLOTATION OF MINERALS. | DOW CHEMICAL CO (US) | 1993-09-29 | — | — | EP | disclosed |
| US-5171427-A | Recovering of minerals by froth flotation | THE DOW CHEMICAL COMPANY (US) | 1992-12-15 | — | — | US | disclosed |
| WO-1992011091-A1 | ARYL MONOSULFONATE COLLECTORS USEFUL IN THE FLOTATION OF MINERALS | THE DOW CHEMICAL COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |
| US-4091088-A | Phenolic amino-carboxylic acid complexes for forming radiopharmaceuticals | AUSTRALIAN ATOMIC ENERGY COMMISSION (AU) | 1978-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172242-A1 | GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF | GHSR, GHRHR, GIPR | SMN1; SMN2 1706/4885HIF1A 1595/4885GLRA1 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.