Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284619 | 0.79 | CCR8 (0.53) | GABRA1GABRG2GABRB3LMNAGABRB2 | |
| SCHEMBL8604129 | 0.76 | CCR8 (0.33) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8602787 | 0.76 | MAPT (0.55) | ALDH1A1MAPTCYP1A2HPGDTSHR | |
| SCHEMBL8600076 | 0.75 | ADRB3 (0.37) | ALDH1A1MAPTCA1CA2CYP1A2 | |
| SCHEMBL8600228 | 0.73 | ALDH1A1 (0.32) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2611040 | 0.73 | AHR (0.50) | GABRA1GABRG2GABRB3LMNAGABRB2 | |
| SCHEMBL18999655 | 0.73 | PARP14 (0.50) | GABRA1GABRG2GABRB3LMNAGABRB2 | |
| SCHEMBL18999654 | 0.72 | CCR8 (0.33) | ALDH1A1MAPTL3MBTL1GABRA1GABRG2 | |
| SCHEMBL8603311 | 0.71 | HTR2A (0.46) | ALDH1A1MAPTL3MBTL1LMNACYP1A2 | |
| SCHEMBL8604191 | 0.71 | GAA (0.35) | ALDH1A1MAPTL3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |