Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600076 | 0.81 | ADRB3 (0.37) | HTR2AALDH1A1MAPTPOLBGAA | |
| SCHEMBL29052296 | 0.79 | KDM4E (0.57) | HTR2AKDM4EALDH1A1HPGDHTR6 | |
| SCHEMBL8602787 | 0.76 | MAPT (0.55) | HTR2AALDH1A1HPGDMAPTPOLB | |
| SCHEMBL594125 | 0.73 | BCHE (0.56) | HTR2AKDM4EALDH1A1HPGDPSMB8 | |
| SCHEMBL593491 | 0.72 | KDM4E (0.42) | HTR2AKDM4EALDH1A1HPGDHTR6 | |
| SCHEMBL8604191 | 0.71 | GAA (0.35) | KDM4EALDH1A1DYRK1AMEN1KMT2A | |
| SCHEMBL8601952 | 0.71 | ALDH1A1 (0.38) | ALDH1A1HPGDMAPTPOLBGAA | |
| SCHEMBL8926562 | 0.70 | HTR2A (0.57) | HTR2AKDM4EALDH1A1HPGDHTR6 | |
| SCHEMBL8603592 | 0.70 | RXFP1 (0.38) | KDM4EALDH1A1NQO2MAPTPOLB | |
| SCHEMBL28325027 | 0.70 | KDM4E (0.62) | HTR2AKDM4EALDH1A1HPGDHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |