Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603621 | 0.93 | ALDH1A1 (0.48) | ALDH1A1HSD17B10KDM4EKMT2AKCNA5 | |
| SCHEMBL8604553 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EKMT2ATDP1 | |
| SCHEMBL8601740 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EKMT2ATDP1 | |
| SCHEMBL8603718 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EKMT2ATDP1 | |
| SCHEMBL8602013 | 0.73 | KMT2A (0.41) | ALDH1A1KDM4EKMT2ATDP1HPGD | |
| SCHEMBL8603481 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4EPTGES2 | |
| SCHEMBL8604561 | 0.72 | ALDH1A1 (0.44) | ALDH1A1HSD17B10KDM4EKMT2APTGES2 | |
| SCHEMBL8602010 | 0.72 | SLC6A4 (0.46) | ALDH1A1KDM4EKMT2AHPGDSLC6A4 | |
| SCHEMBL8603459 | 0.70 | ALDH1A1 (0.44) | ALDH1A1HSD17B10KDM4EKMT2ATDP1 | |
| SCHEMBL8604539 | 0.70 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4EKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |