Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | OGG1 | O15527 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603619 | 0.93 | SLC6A2 (0.43) | KMT2ASLC6A2SLC6A4ALDH1A1HPGD | |
| SCHEMBL8604551 | 0.82 | KDM4E (0.42) | KMT2AALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL8603717 | 0.77 | BTN3A1 (0.39) | SLC6A2SLC6A4ALDH1A1HPGDKDM4E | |
| SCHEMBL8601739 | 0.77 | HTT (0.46) | KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL8602010 | 0.76 | SLC6A4 (0.46) | KMT2ASLC6A2SLC6A4ALDH1A1HPGD | |
| SCHEMBL8602015 | 0.73 | ALDH1A1 (0.45) | KMT2ASLC6A2SLC6A4ALDH1A1HPGD | |
| SCHEMBL10390030 | 0.71 | TSHR (0.51) | KMT2AALDH1A1HPGDKDM4ETSHR | |
| SCHEMBL10389728 | 0.71 | PPARG (0.49) | SLC6A2SLC6A4ALDH1A1HPGDKDM4E | |
| SCHEMBL8603456 | 0.69 | LMNA (0.37) | KMT2ASLC6A2SLC6A4ALDH1A1HPGD | |
| SCHEMBL6707311 | 0.67 | TSHR (0.47) | KMT2AALDH1A1HPGDKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |