Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603616 | 0.91 | SLC6A4 (0.47) | SLC6A4SLC6A2KMT2APSMB5PPARG | |
| SCHEMBL8599327 | 0.86 | SLC6A4 (0.52) | SLC6A4SLC6A2KMT2APPARGPPARA | |
| SCHEMBL8602034 | 0.81 | KMT2A (0.41) | SLC6A4SLC6A2KMT2APSMB5PPARG | |
| SCHEMBL8604548 | 0.81 | MMP8 (0.43) | SLC6A4SLC6A2KMT2APSMB5PPARG | |
| SCHEMBL8601737 | 0.77 | GAA (0.48) | SLC6A4SLC6A2KMT2APSMB5PPARG | |
| SCHEMBL8603715 | 0.77 | SLC6A4 (0.39) | SLC6A4SLC6A2KMT2APSMB5PPARG | |
| SCHEMBL8602013 | 0.76 | KMT2A (0.41) | SLC6A4SLC6A2KMT2APSMB5KDM4E | |
| SCHEMBL8604557 | 0.73 | SLC6A4 (0.45) | SLC6A4SLC6A2PPARGPPARAKDM4E | |
| SCHEMBL27478671 | 0.73 | PPARG (0.51) | SLC6A4SLC6A2KMT2APSMB5PPARG | |
| SCHEMBL8603475 | 0.73 | SLC6A2 (0.42) | SLC6A4SLC6A2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |