Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602149 | 1.00 | HTR2A (0.47) | HTR2ARAB9AIDO1L3MBTL1DPP8 | |
| Hydrochloric Acid SCHEMBL8600189 | 0.99 | IDO1 (0.48) | HTR2ARAB9AIDO1L3MBTL1DPP8 | |
| Hydrochloric Acid SCHEMBL8603825 | 0.99 | IDO1 (0.48) | HTR2ARAB9AIDO1L3MBTL1DPP8 | |
| SCHEMBL27542540 | 0.84 | IDO1 (0.51) | HTR2ARAB9AIDO1DPP8DPP9 | |
| SCHEMBL3391449 | 0.83 | GAA (0.50) | HTR2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL3391445 | 0.83 | GAA (0.50) | HTR2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL9763703 | 0.83 | DPP8 (0.51) | HTR2ARAB9AIDO1L3MBTL1DPP8 | |
| Hydrochloric Acid SCHEMBL10434967 | 0.82 | DPP8 (0.50) | HTR2ARAB9AIDO1L3MBTL1DPP8 | |
| SCHEMBL8350753 | 0.82 | RAB9A (0.52) | HTR2ARAB9AIDO1DPP8DPP9 | |
| SCHEMBL7751248 | 0.81 | MME (0.53) | IDO1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840918-A | PEPTIDOMIMETIC COMPOUNDS USEFUL IN THE TREATMENT OF RAS-ASSOCIATED HUMAN CANCERS | EISAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0750609-A4 | ISOPRENYL TRANSFERASE INHIBITORS | EISAI CO LTD (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0750609-A1 | ISOPRENYL TRANSFERASE INHIBITORS | Eisai Co., Ltd. (JP) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995025086-A1 | ISOPRENYL TRANSFERASE INHIBITORS | EISAI CO., LTD. (JP) | 1995-09-21 | — | — | WO | disclosed |