Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | BCL9 | O00512 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391449 | 1.00 | GAA (0.50) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL8602153 | 0.83 | HTR2A (0.47) | HTR2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8602149 | 0.83 | HTR2A (0.47) | HTR2AALDH1A1MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8603825 | 0.82 | IDO1 (0.48) | HTR2AALDH1A1MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8600189 | 0.82 | IDO1 (0.48) | HTR2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12229225 | 0.82 | LMNA (0.43) | GAAALDH1A1KMT2A | |
| SCHEMBL12229268 | 0.82 | LMNA (0.43) | GAAALDH1A1KMT2A | |
| SCHEMBL7787944 | 0.82 | BCL9 (0.57) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL9840744 | 0.81 | BCL9 (0.50) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL7275811 | 0.81 | BCL9 (0.50) | GAABCL9CTNNB1HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635878-B1 | PEPTIDE CONJUGATE FOR MAGNETIC RESONANCE IMAGING OF MATRIX METALLOPROTEINASES | GUERBET SA (FR) | 2010-12-29 | — | — | EP | disclosed |
| CN-101868180-A | imaging particles | UNIV ST LOUIS | 2010-10-20 | — | — | CN | disclosed |
| EP-1684724-A4 | ENHANCED DRUG DELIVERY | BARNES JEWISH HOSPITAL (US) | 2008-04-02 | — | — | EP | disclosed |
| EP-1572639-A4 | INTEGRIN TARGETED IMAGING AGENTS | BARNES JEWISH HOSPITAL (US) | 2006-08-09 | — | — | EP | disclosed |
| EP-1684724-A2 | ENHANCED DRUG DELIVERY | Barnes-Jewish Hospital (US) | 2006-08-02 | — | — | EP | disclosed |
| EP-1635878-A2 | PEPTIDE CONJUGATE FOR MAGNETIC RESONANCE IMAGING | GUERBET (FR) | 2006-03-22 | — | — | EP | disclosed |
| EP-1572639-A1 | INTEGRIN TARGETED IMAGING AGENTS | Barnes Jewish Hospital (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2005051305-A2 | ENHANCED DRUG DELIVERY | BARNES-JEWISH HOSPITAL (US) | 2005-06-09 | — | — | WO | disclosed |
| WO-2004112840-A2 | PEPTIDE CONJUGATE FOR MAGNETIC RESONANCE IMAGING | GUERBET (FR) | 2004-12-29 | — | — | WO | disclosed |
| WO-2003062198-A1 | INTEGRIN TARGETED IMAGING AGENTS | BARNES JEWISH HOSPITAL (US) | 2003-07-31 | — | — | WO | disclosed |