Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600001 | 0.97 | CNR1 (0.40) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8603224 | 0.85 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL8601087 | 0.81 | PDE4A (0.47) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8601171 | 0.79 | NR1D1 (0.40) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL8599642 | 0.76 | PDE4A (0.44) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8601399 | 0.76 | MEN1 (0.39) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1553899 | 0.76 | SLC22A12 (0.54) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8572419 | 0.75 | PDE4A (0.49) | BRD4PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL8602666 | 0.75 | SLC22A12 (0.53) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8601071 | 0.74 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |