Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CPB1 | P15086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602186 | 0.80 | ADORA3 (0.42) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL17761318 | 0.78 | ADORA3 (0.43) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL28114415 | 0.75 | ADORA3 (0.47) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL2436013 | 0.75 | GAA (0.43) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL7355559 | 0.74 | TBXAS1 (0.44) | LMNAHTTHPGD | |
| Pyrazine SCHEMBL4235261 | 0.73 | KDM4E (0.45) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL25660372 | 0.73 | KDM4E (0.45) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL16150119 | 0.72 | KDM4E (0.41) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL11678794 | 0.72 | KDM4E (0.48) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL7363501 | 0.72 | KDM4E (0.50) | KDM4ENAPRTLMNACPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807859-A | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1998-09-15 | — | — | US | disclosed |