Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 16/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476790 | 0.92 | TSHR (0.45) | TSHRHTTALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8552777 | 0.91 | ALDH1A1 (0.45) | TSHRALDH1A1SMN1; SMN2PPARGTP53 | |
| SCHEMBL8601638 | 0.87 | TSHR (0.44) | TSHRALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8556015 | 0.86 | HTT (0.53) | TSHRHTTPPARG | |
| SCHEMBL8602935 | 0.85 | TSHR (0.46) | TSHRHTTALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8555379 | 0.85 | PPARG (0.48) | TSHRHTTALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8602443 | 0.84 | HTT (0.51) | TSHRHTTALDH1A1PPARG | |
| SCHEMBL7471327 | 0.84 | TP53 (0.40) | TSHRHTTALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8599910 | 0.83 | GSK3B (0.42) | PPARGTP53 | |
| SCHEMBL7470321 | 0.82 | NPFFR1 (0.36) | TSHRHTTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | claimed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | claimed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |