Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 7/20 | 0.38 |
| ▸ | RXRB | P28702 | 6/20 | 0.38 |
| ▸ | RXRG | P48443 | 5/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603482 | 0.83 | ALDH1A1 (0.36) | ALDH1A1HTTLMNASMN1; SMN2GAA | |
| SCHEMBL8601740 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HTTLMNAGAAMEN1 | |
| SCHEMBL8603481 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HTTMCL1POLBKDM4E | |
| SCHEMBL8604539 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HTTLMNAGAAMEN1 | |
| SCHEMBL8604561 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HTTLMNAKMT2APOLB | |
| SCHEMBL8602990 | 0.72 | GAA (0.44) | ALDH1A1HTTRXRARXRBRXRG | |
| SCHEMBL9377864 | 0.66 | RXRA (0.47) | ALDH1A1RXRARXRBRXRGMCL1 | |
| SCHEMBL8603718 | 0.64 | ALDH1A1 (0.47) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL8600745 | 0.64 | PTGIR (0.40) | ALDH1A1GAA | |
| SCHEMBL24440183 | 0.63 | SSTR4 (0.58) | RXRARXRBRXRGMCL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |