Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 13/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600743 | 0.87 | PTGIR (0.55) | PTGIR | |
| SCHEMBL8414288 | 0.74 | MTNR1A (0.48) | PTGIRMTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL8414324 | 0.73 | MTNR1A (0.47) | PTGIRMTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL8812824 | 0.73 | PTGIR (0.47) | PTGIRMTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL8602824 | 0.71 | PTGIR (0.50) | PTGIRCA1CA2ACHE | |
| SCHEMBL8602826 | 0.71 | PTGIR (0.50) | PTGIRCA1CA2ACHE | |
| SCHEMBL9045690 | 0.70 | CHRM2 (0.48) | PTGIRMTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL8811681 | 0.70 | PTGIR (0.47) | PTGIRMTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL9045695 | 0.68 | MTNR1A (0.44) | PTGIRMTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL9017303 | 0.67 | DRD2 (0.67) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | claimed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5624959-A | INHIBITING UTERINE CONTRACTIONS, PROSTAGLANDIN ANTAGONIST OR AGONIST, ANALGESICS AND ANTISECRETORY AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |