Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16433913 | 0.81 | GAA (0.46) | ALDH1A1HPGDGAANPC1RAB9A | |
| SCHEMBL5438762 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HPGDGAAPOLBGFER | |
| SCHEMBL5426181 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDGAANPC1RAB9A | |
| SCHEMBL6502344 | 0.77 | ALDH1A1 (0.51) | ALDH1A1HPGDGAAPOLBL3MBTL1 | |
| SCHEMBL3521491 | 0.75 | TDP1 (0.56) | ALDH1A1HPGDL3MBTL1GFERMEN1 | |
| SCHEMBL15289351 | 0.74 | ALDH1A1 (0.47) | ALDH1A1HPGDGAANPC1RAB9A | |
| SCHEMBL8178332 | 0.72 | GSK3A (0.50) | ALDH1A1HPGDGAANPC1RAB9A | |
| SCHEMBL3520528 | 0.72 | L3MBTL1 (0.66) | ALDH1A1GAANPC1RAB9APOLB | |
| SCHEMBL8414098 | 0.71 | TSHR (0.47) | ALDH1A1HPGDGAANPC1RAB9A | |
| SCHEMBL7695139 | 0.71 | ALDH1A1 (1.00) | ALDH1A1HPGDGAAPOLBGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767275-A | Preparation of triazolone compounds | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1998-06-16 | — | — | US | disclosed |
| EP-0668857-B1 | PROCESS FOR THE PREPARATION OF TRIAZOLONE COMPOUNDS | ACRAF (IT) | 1998-02-25 | — | — | EP | disclosed |
| EP-0668857-A1 | PROCESS FOR THE PREPARATION OF TRIAZOLONE COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (IT) | 1995-08-30 | — | — | EP | disclosed |
| WO-1994011357-A1 | PROCESS FOR THE PREPARATION OF TRIAZOLONE COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO (A.C.R.A.F.) S.P.A. (IT) | 1994-05-26 | — | — | WO | disclosed |