Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | MMP12 | P39900 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 7/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603483 | 0.80 | GAA (0.43) | PPARGPPARA | |
| SCHEMBL8604548 | 0.80 | MMP8 (0.43) | MMP8MMP12MMP13MMP1MMP7 | |
| SCHEMBL8604098 | 0.72 | MMP8 (0.41) | MMP8MMP12MMP13MMP1MMP7 | |
| SCHEMBL8604101 | 0.70 | ITGB3 (0.35) | MMP8MMP12MMP13MMP1MMP7 | |
| SCHEMBL8414123 | 0.70 | C3AR1 (0.33) | — | |
| SCHEMBL8411289 | 0.66 | PPARG (0.34) | PPARGPPARA | |
| SCHEMBL8414351 | 0.66 | PTGIR (0.30) | — | |
| SCHEMBL8414339 | 0.65 | PPARG (0.34) | PPARGPPARA | |
| SCHEMBL8603616 | 0.65 | SLC6A4 (0.47) | PPARGPPARA | |
| SCHEMBL8623405 | 0.65 | PTGIR (0.56) | MMP8MMP12MMP13MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |