Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 3/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 6/20 | 0.49 |
| ▸ | CA2 | P00918 | 6/20 | 0.49 |
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 5/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.49 |
| ▸ | CA3 | P07451 | 3/20 | 0.49 |
| ▸ | CA4 | P22748 | 3/20 | 0.49 |
| ▸ | CA6 | P23280 | 3/20 | 0.49 |
| ▸ | CA5A | P35218 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875776 | 0.87 | HPGD (0.46) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL31504508 | 0.87 | ALOX5 (0.51) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL4291415 | 0.85 | CA2 (0.50) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL9815588 | 0.79 | CA2 (0.59) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL468315 | 0.77 | CA1 (0.55) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL11853542 | 0.76 | CA1 (0.55) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6311444 | 0.75 | ALDH1A1 (0.55) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL22038769 | 0.75 | POLB (0.59) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL1242007 | 0.74 | ALDH1A1 (0.48) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL10615659 | 0.74 | POLB (0.51) | POLBF2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5777137-A | Pancratistatins and processes for their production | UNIVERSITY OF FLORIDA (US) | 1998-07-07 | — | — | US | disclosed |
| WO-1997016453-A2 | PANCRATISTATINS AND PROCESSES FOR THEIR PRODUCTION | UNIVERSITY OF FLORIDA (US) | 1997-05-09 | — | — | WO | disclosed |