Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 10/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469217 | 0.90 | CHEK2 (0.47) | CHEK2HSP90AA1ESR2TDP1NR4A2 | |
| SCHEMBL8604368 | 0.81 | CHEK2 (0.61) | CHEK2HSP90AA1ESR2TDP1NR4A2 | |
| SCHEMBL5217725 | 0.79 | CHEK2 (0.87) | CHEK2NR4A2NPBWR1MMP2MMP9 | |
| SCHEMBL3167456 | 0.78 | CHEK2 (0.57) | CHEK2HSP90AA1ESR2TDP1NR4A2 | |
| SCHEMBL8602741 | 0.78 | CHEK2 (0.57) | CHEK2HSP90AA1ESR2TDP1NR4A2 | |
| SCHEMBL8602093 | 0.76 | MMP2 (0.64) | CHEK2HSP90AA1ESR2TDP1NR4A2 | |
| SCHEMBL20982644 | 0.75 | NR4A2 (0.86) | CHEK2HSP90AA1ESR2TDP1NR4A2 | |
| SCHEMBL8600314 | 0.75 | CHEK2 (0.60) | CHEK2HSP90AA1ESR2TDP1NR4A2 | |
| SCHEMBL20982607 | 0.75 | CHEK2 (0.63) | CHEK2HSP90AA1ESR2TDP1NR4A2 | |
| SCHEMBL8601919 | 0.75 | CHEK2 (0.60) | CHEK2HSP90AA1ESR2TDP1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |