Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607230 | 0.80 | DRD2 (0.53) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8606011 | 0.78 | MEN1 (0.44) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2105563 | 0.73 | MAPT (0.47) | MAPTKDM4EIRAK4ALDH1A1LMNA | |
| SCHEMBL3797765 | 0.73 | MAPT (0.47) | MAPTKDM4EIRAK4ALDH1A1LMNA | |
| SCHEMBL8606738 | 0.73 | MAPT (0.44) | MAPTKDM4EIRAK4ALDH1A1LMNA | |
| SCHEMBL19795361 | 0.73 | CHRNA7 (0.45) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8607529 | 0.72 | MAPT (0.46) | MAPTKDM4EIRAK4ALDH1A1LMNA | |
| SCHEMBL8606018 | 0.72 | MAPT (0.45) | MAPTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL657283 | 0.71 | MAPT (0.47) | MAPTKDM4EIRAK4ALDH1A1LMNA | |
| SCHEMBL3055880 | 0.71 | MGLL (0.56) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789595-A | ANTICOAGULANTS | TERUMO KABUSHIKI KAISHA (JP) | 1998-08-04 | — | — | US | disclosed |
| CN-1167485-A | Tetrahydroisoquinoline derivative and medicinal preparation containing the same | TERUMO CORP (JP) | 1997-12-10 | — | — | CN | disclosed |
| EP-0790247-A1 | TETRAHYDROISOQUINOLINE DERIVATIVE AND MEDICINAL PREPARATION CONTAINING THE SAME | TERUMO KABUSHIKI KAISHA (JP) | 1997-08-20 | — | — | EP | disclosed |