Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.32 |
| ▸ | FEN1 | P39748 | 8/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PARG | Q86W56 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604780 | 0.78 | HTT (0.41) | MAPTSMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL8603093 | 0.77 | MAPT (0.32) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8780760 | 0.74 | ACLY (0.33) | MAPTLMNA | |
| SCHEMBL8536463 | 0.69 | NSD2 (0.43) | NSD2MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL18739952 | 0.66 | BRD4 (0.50) | NSD2MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL8606043 | 0.66 | NSD2 (0.40) | NSD2MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL9634888 | 0.66 | MAPT (0.36) | NSD2MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL20807647 | 0.65 | NSD2 (0.45) | NSD2MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL17507368 | 0.65 | MEN1 (0.54) | NSD2MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL22408917 | 0.64 | NSD2 (0.38) | NSD2MAPTLMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854179-A | Sulfur-substituted phenylsulfonylureas, processes for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-29 | — | — | US | disclosed |
| EP-0790985-A1 | N-ACYL-N-ALKYLAMINO PHENYL SULPHONYL UREAS WITH SULPHUR SUBSTITUENTS, PROCESS FOR THEIR PRODUCTION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Hoechst Schering AgrEvo GmbH (DE) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014304-A1 | N-ACYL-N-ALKYLAMINO PHENYL SULPHONYL UREAS WITH SULPHUR SUBSTITUENTS, PROCESS FOR THEIR PRODUCTION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1996-05-17 | — | — | WO | disclosed |