Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PARG | Q86W56 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028383 | 0.67 | ALDH1A1 (0.44) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL6582730 | 0.67 | ALDH1A1 (0.45) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8606047 | 0.66 | NSD2 (0.38) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL21028198 | 0.65 | ALDH1A1 (0.43) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL21527808 | 0.64 | ALOX5AP (0.37) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL21925677 | 0.64 | BRD4 (0.40) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8604780 | 0.63 | HTT (0.41) | MAPTSMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL2863381 | 0.62 | HSD17B10 (0.36) | MAPTLMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL19590542 | 0.62 | MEN1 (0.42) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL24429352 | 0.61 | LMNA (0.43) | MAPTLMNASMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096484-A | SULPHONYLUREA-TYPE HERBICIDES | RHONE-POULENC AGROCHIMIE (FR) | 1992-03-17 | — | — | US | disclosed |
| US-4960454-A | Sulphonylurea-type herbicides | RHONE-POULENC AGROCHIMIE (FR) | 1990-10-02 | — | — | US | disclosed |