Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602639 | 0.82 | CA12 (0.32) | LMNA | |
| SCHEMBL8606047 | 0.77 | NSD2 (0.38) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8604780 | 0.74 | HTT (0.41) | MAPTSMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL8602857 | 0.72 | ALDH1A1 (0.38) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8606473 | 0.71 | CDK1 (0.60) | MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL8780760 | 0.70 | ACLY (0.33) | MAPTLMNA | |
| SCHEMBL8603091 | 0.69 | ALDH1A1 (0.35) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8661476 | 0.64 | CDK1 (0.45) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL7688335 | 0.63 | CDK1 (0.57) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL9634888 | 0.62 | MAPT (0.36) | MAPTLMNASMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854179-A | Sulfur-substituted phenylsulfonylureas, processes for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-29 | — | — | US | disclosed |