SCHEMBL8606145

SCHEMBL8606145

CC1(C2=C(C(=O)c3ccccc3S(C)(=O)=O)C(Cl)N(Cl)O2)CC1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
BCAT2 O15382 1/20 0.35
EED O75530 1/20 0.33
NAAA Q02083 1/20 0.30
NAMPT P43490 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8608337 0.87 EED (0.36) LMNABCAT2EEDNAMPT
SCHEMBL8609593 0.74 BCAT2 (0.36) LMNABCAT2EED
SCHEMBL8684225 0.73 TSHR (0.33) LMNABCAT2EEDNAMPT
SCHEMBL8605528 0.71 LMNA (0.42) LMNABCAT2EEDNAAANAMPT
SCHEMBL8607785 0.68 LMNA (0.37) LMNABCAT2EED
SCHEMBL8493444 0.68 BCAT2 (0.39) LMNABCAT2EEDNAMPT
SCHEMBL4321077 0.68 BCAT2 (0.59) LMNABCAT2EED
SCHEMBL8605534 0.68 BCAT2 (0.36) LMNABCAT2EEDNAMPT
SCHEMBL8488843 0.68 BCAT2 (0.39) LMNABCAT2EED
SCHEMBL8608675 0.65 LMNA (0.38) LMNABCAT2EED

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5804532-A REACTING A BENZOYL ISOXAZOLE WITH A BASE RHONE-POULENC AGRICULTURE LIMITED (GB) 1998-09-08 US disclosed