Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8606145 | 0.87 | LMNA (0.37) | EEDLMNABCAT2NAMPT | |
| SCHEMBL8607785 | 0.80 | LMNA (0.37) | EEDLMNABCAT2CA1CA2 | |
| SCHEMBL8684225 | 0.78 | TSHR (0.33) | EEDLMNABCAT2NAMPT | |
| SCHEMBL8609593 | 0.72 | BCAT2 (0.36) | EEDLMNABCAT2 | |
| SCHEMBL8488843 | 0.70 | BCAT2 (0.39) | EEDLMNABCAT2MEN1NPC1 | |
| SCHEMBL8607350 | 0.70 | BCAT2 (0.38) | EEDLMNABCAT2CA1CA2 | |
| SCHEMBL8605528 | 0.70 | LMNA (0.42) | EEDLMNABCAT2NAMPTRAB9A | |
| SCHEMBL8491655 | 0.70 | TSHR (0.37) | EEDLMNABCAT2CA1CA2 | |
| SCHEMBL8491543 | 0.67 | TSHR (0.35) | EEDLMNABCAT2 | |
| SCHEMBL8493444 | 0.66 | BCAT2 (0.39) | EEDLMNABCAT2NAMPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |