Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7298994 | 0.99 | DRD2 (0.49) | DRD2SIGMAR1SMN1; SMN2RAB9AGRIN1 | |
| SCHEMBL12549292 | 0.93 | SMN1; SMN2 (0.48) | DRD2SIGMAR1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8607230 | 0.89 | DRD2 (0.53) | DRD2SIGMAR1SMN1; SMN2GRIN1GRIN2B | |
| SCHEMBL14558962 | 0.88 | DRD2 (0.54) | DRD2SIGMAR1SMN1; SMN2RAB9AGRIN1 | |
| SCHEMBL27927942 | 0.83 | GRIN1 (0.51) | DRD2SIGMAR1SMN1; SMN2GRIN1GRIN2B | |
| SCHEMBL14879191 | 0.81 | GRIN1 (0.54) | DRD2SIGMAR1GRIN1GRIN2BALDH1A1 | |
| SCHEMBL3910177 | 0.81 | NR1H2 (0.49) | SIGMAR1SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL8798709 | 0.80 | DPP7 (0.48) | DRD2SIGMAR1SMN1; SMN2RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7832755 | 0.80 | GRIN1 (0.53) | DRD2SIGMAR1SMN1; SMN2GRIN1GRIN2B | |
| SCHEMBL1295027 | 0.79 | ALDH1A1 (0.61) | SMN1; SMN2RAB9AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789595-A | ANTICOAGULANTS | TERUMO KABUSHIKI KAISHA (JP) | 1998-08-04 | — | — | US | claimed |
| US-5789595-A | ANTICOAGULANTS | TERUMO KABUSHIKI KAISHA (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0790247-A1 | TETRAHYDROISOQUINOLINE DERIVATIVE AND MEDICINAL PREPARATION CONTAINING THE SAME | TERUMO KABUSHIKI KAISHA (JP) | 1997-08-20 | — | — | EP | disclosed |