Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608562 | 0.82 | NR1H2 (0.46) | DPP7MAPTKDM4ESIGMAR1ALDH1A1 | |
| SCHEMBL8606342 | 0.80 | DRD2 (0.50) | DPP7MAPTLMNASIGMAR1DRD2 | |
| SCHEMBL38658114 | 0.80 | DPP7 (0.51) | DPP7MAPTLMNASIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7298994 | 0.79 | DRD2 (0.49) | DPP7MAPTLMNASIGMAR1DRD2 | |
| SCHEMBL8607230 | 0.78 | DRD2 (0.53) | MAPTKDM4ESIGMAR1DRD2ALDH1A1 | |
| SCHEMBL8798204 | 0.78 | AKR1C3 (0.45) | DPP7MAPTLMNAKDM4ESIGMAR1 | |
| SCHEMBL30561509 | 0.78 | PNMT (0.47) | DPP7MAPTLMNAKDM4EDRD2 | |
| SCHEMBL1951319 | 0.78 | PNMT (0.47) | DPP7MAPTLMNAKDM4EDRD2 | |
| SCHEMBL12549292 | 0.78 | SMN1; SMN2 (0.48) | MAPTLMNAKDM4ESIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL7511812 | 0.77 | DPP7 (0.46) | DPP7MAPTLMNAKDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790247-A1 | TETRAHYDROISOQUINOLINE DERIVATIVE AND MEDICINAL PREPARATION CONTAINING THE SAME | TERUMO KABUSHIKI KAISHA (JP) | 1997-08-20 | — | — | EP | disclosed |