Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489172 | 0.86 | TSHR (0.37) | BCAT2EEDLMNACA1CA2 | |
| SCHEMBL8488843 | 0.76 | BCAT2 (0.39) | BCAT2EEDLMNAMEN1NPC1 | |
| SCHEMBL8491655 | 0.75 | TSHR (0.37) | BCAT2EEDLMNACA1CA2 | |
| SCHEMBL8491954 | 0.72 | LMNA (0.36) | BCAT2EEDLMNAMAPK1CACNA1B | |
| SCHEMBL8607785 | 0.71 | LMNA (0.37) | BCAT2EEDLMNACA1CA2 | |
| SCHEMBL4321077 | 0.71 | BCAT2 (0.59) | BCAT2EEDLMNACA1CA2 | |
| SCHEMBL8684225 | 0.70 | TSHR (0.33) | BCAT2EEDLMNA | |
| SCHEMBL8608337 | 0.70 | EED (0.36) | BCAT2EEDLMNACA1CA2 | |
| SCHEMBL26124963 | 0.67 | BCAT2 (0.51) | BCAT2EEDLMNACA1CA2 | |
| SCHEMBL8608708 | 0.66 | LMNA (0.38) | BCAT2EEDLMNACACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |