Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460636 | 0.85 | KMT2A (0.42) | HTTKMT2AMAPTMEN1USP2 | |
| SCHEMBL8458962 | 0.82 | KMT2A (0.45) | HTTKMT2AMAPTMEN1USP2 | |
| SCHEMBL8460350 | 0.77 | MEN1 (0.48) | HTTKMT2AMAPTMEN1USP2 | |
| SCHEMBL5136133 | 0.70 | SMN1; SMN2 (0.50) | HTTKMT2AMAPTMEN1NPC1 | |
| SCHEMBL30142666 | 0.69 | NPC1 (0.66) | KMT2AMAPTMEN1USP2CYP2C9 | |
| SCHEMBL17732650 | 0.66 | ADORA3 (0.53) | HTTKMT2AMAPTMEN1USP2 | |
| SCHEMBL5797626 | 0.64 | RAB9A (0.56) | HTTKMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL11831465 | 0.64 | MEN1 (0.64) | HTTKMT2AMAPTMEN1CYP2C9 | |
| SCHEMBL1804666 | 0.63 | NPC1 (0.76) | HTTKMT2AMAPTMEN1NSD2 | |
| SCHEMBL17732536 | 0.62 | POLB (0.56) | HTTKMT2AMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935591-A | Method for treatment of equine protozoal myeloencephalitis with thiazolides | ROMARK LABORATORIES, L.C. (US) | 1999-08-10 | — | — | US | claimed |