Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 2/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.37 |
| ▸ | NT5C2 | P49902 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL250054 | 0.90 | ALDH1A1 (0.55) | ALDH1A1EGFRLMNAGAAKDM4E | |
| Adenine SCHEMBL8607560 | 0.89 | PI4KA (0.51) | ALDH1A1EGFRPI4KAPI4K2BPI4K2A | |
| Hypoxanthine SCHEMBL1266881 | 0.85 | ALDH1A1 (0.62) | ALDH1A1LMNAGDAAKR1C1BRD4 | |
| Adenine SCHEMBL250055 | 0.84 | PI4KA (0.56) | ALDH1A1EGFRPI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL8820860 | 0.81 | ALDH1A1 (0.58) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL27168508 | 0.78 | EGFR (0.44) | ALDH1A1EGFRLMNAGDAGAA | |
| Adenine SCHEMBL4299753 | 0.76 | KMT2A (0.57) | ALDH1A1EGFRLMNABRD4KDM4E | |
| Adenine SCHEMBL8469554 | 0.72 | ALDH1A1 (0.43) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL14125907 | 0.72 | PI4KA (0.39) | ALDH1A1EGFRPI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL18321272 | 0.72 | GDA (0.43) | PI4KAPI4K2BPI4K2API4KBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780256-A | REACTING WITH AMINO ACID DEHYDROGENASE IN PRESENCE OF THIO-NADP OR THIO-NAD AND OTHER COENZYMES | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1998-07-14 | — | — | US | claimed |
| EP-0632133-B1 | HIGHLY SENSITIVE DETERMINATION OF D-3-HYDROXYBUTYRIC ACID OR ACETOACETIC ACID AND COMPOSITION THEREFOR | ASAHI CHEMICAL IND (JP) | 1998-04-22 | — | — | EP | claimed |
| US-5633143-A | Method for the quantitative determination of D-3-hydroxybutyric acid and acetoacetic acid, and analytical reagent therefor | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-05-27 | — | — | US | claimed |
| EP-0632133-A1 | HIGHLY SENSITIVE DETERMINATION OF D-3-HYDROXYBUTYRIC ACID OR ACETOACETIC ACID AND COMPOSITION THEREFOR | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-01-04 | — | — | EP | claimed |