Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 6/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MYLK | Q15746 | 1/20 | 0.36 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAPGEF3 | O95398 | 3/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412822 | 0.73 | P2RX1 (0.38) | P2RX1TMPRSS4P2RX4P2RX7MEN1 | |
| SCHEMBL8606563 | 0.72 | P2RX1 (0.35) | P2RX1TMPRSS4P2RX4P2RX7CYP11B1 | |
| SCHEMBL3028484 | 0.65 | CES2 (0.46) | MEN1KMT2AGAADDR1 | |
| SCHEMBL8608917 | 0.65 | KMT2A (0.49) | MEN1KMT2AKDR | |
| SCHEMBL28095379 | 0.65 | CES2 (0.49) | MEN1KMT2AGRIK1GAADDR1 | |
| SCHEMBL8490842 | 0.65 | CYP2C19 (0.42) | GAADDR1 | |
| SCHEMBL10334495 | 0.64 | SMN1; SMN2 (0.57) | MEN1KMT2AGRIK1 | |
| SCHEMBL8607500 | 0.64 | SMN1; SMN2 (0.42) | MEN1KMT2AKDR | |
| SCHEMBL8017606 | 0.64 | MAOB (0.42) | MEN1KMT2AKDR | |
| SCHEMBL6751351 | 0.64 | CES2 (0.47) | GAADDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |