Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 4/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MYLK | Q15746 | 1/20 | 0.33 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.33 |
| ▸ | CLPP | Q16740 | 1/20 | 0.33 |
| ▸ | RHOC | P08134 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412822 | 0.74 | P2RX1 (0.38) | P2RX1P2RX4P2RX7TMPRSS4DDR1 | |
| SCHEMBL8607647 | 0.72 | P2RX1 (0.38) | P2RX1P2RX4P2RX7TMPRSS4DDR1 | |
| SCHEMBL14893085 | 0.64 | CES2 (0.64) | P2RX1RHOCRHOANOTUM | |
| SCHEMBL8608917 | 0.62 | KMT2A (0.49) | GABRA1GABRG2GABRB3GABRB1GABRB2 | |
| SCHEMBL10334495 | 0.62 | SMN1; SMN2 (0.57) | MEN1KMT2ANOTUM | |
| SCHEMBL8607500 | 0.62 | SMN1; SMN2 (0.42) | MEN1KDRKMT2A | |
| SCHEMBL5274963 | 0.62 | CES2 (0.55) | P2RX1MEN1KMT2ANOTUM | |
| SCHEMBL8017606 | 0.62 | MAOB (0.42) | MEN1KDRKMT2A | |
| SCHEMBL5843160 | 0.61 | CFTR (0.63) | MEN1KMT2ANOTUM | |
| SCHEMBL4096751 | 0.60 | KDM4E (0.50) | GABRA1GABRG2GABRB3GABRB2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |