Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 7/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12906942 | 0.79 | — | — | |
| SCHEMBL1243195 | 0.77 | HTR2A (0.33) | HTR2CHTR2BHTR1ASLC6A2SLC6A4 | |
| SCHEMBL12477783 | 0.76 | HTR2C (0.47) | HTR2CHTR2BHTR1ASLC6A2SLC6A4 | |
| SCHEMBL12733571 | 0.75 | ALOX5AP (0.39) | — | |
| SCHEMBL10091346 | 0.74 | — | — | |
| SCHEMBL15684659 | 0.74 | HCRTR2 (0.48) | HTR2CHTR2BHTR1ASLC6A2SLC6A4 | |
| SCHEMBL2505519 | 0.74 | HTR2C (0.40) | HTR2CHTR2BHTR1ASLC6A2SLC6A4 | |
| SCHEMBL29487575 | 0.74 | HTR2C (0.40) | HTR2CHTR2BHTR1ASLC6A2SLC6A4 | |
| SCHEMBL14391040 | 0.73 | RIPK1 (0.36) | HTR2CHTR2BHTR1ASLC6A2SLC6A4 | |
| SCHEMBL2511031 | 0.73 | FPR2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750213-A | MOLECULAR ORIENTATION | SHARP KABUSHIKI KAISHA (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5709911-A | Polymerizable compound and liquid crystal display device using the same | SHARP KABUSHIKI KAISHA (JP) | 1998-01-20 | — | — | US | disclosed |