Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607936 | 0.88 | ALOX5 (0.44) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL4729170 | 0.85 | NPC1 (0.45) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL4729172 | 0.85 | NPC1 (0.45) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL8609409 | 0.85 | NPC1 (0.45) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL8613457 | 0.76 | NPC1 (0.44) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL8609455 | 0.75 | NPC1 (0.43) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8309228 | 0.72 | ALOX5 (0.51) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL8309230 | 0.72 | ALOX5 (0.51) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL8610041 | 0.72 | ALOX5 (0.51) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL4728458 | 0.71 | ALOX5 (0.38) | MEN1KMT2ALMNAGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814648-A | N-hydroxyureas as antiinflammatory agents | PFIZER INC. (US) | 1998-09-29 | — | — | US | disclosed |