SCHEMBL8608752

SCHEMBL8608752

CC(=O)OCC(c1ccc(I)cc1)c1ccc(I)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
ALB P02768 1/20 0.38
TPMT P51580 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
ACACB O00763 1/20 0.36
SLC6A3 Q01959 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PDPK1 O15530 1/20 0.35
GSK3B P49841 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
FPR2 P25090 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19426871 0.84 ALDH1A1 (0.35) ALDH1A1TPMTACACBSLC6A3TDP1
SCHEMBL20695032 0.84 ALDH1A1 (0.35) ALDH1A1TPMTACACBSLC6A3TDP1
SCHEMBL416523 0.83 ALDH1A1 (0.46) ALDH1A1CA12CA1CA2CA9
SCHEMBL9601863 0.82 ALDH1A1 (0.53) ALDH1A1CA12CA1CA2CA9
SCHEMBL24333940 0.81 LMNA (0.43) ALDH1A1TDP1CYP1A2CYP2D6NPSR1
SCHEMBL7605459 0.81 CYP1A2 (0.42) ALDH1A1CA12CA1CA2CA9
SCHEMBL7607677 0.76 NPC1 (0.50) ALDH1A1TDP1
SCHEMBL7609839 0.75 SMN1; SMN2 (0.54) ALDH1A1SMN1; SMN2
SCHEMBL8583312 0.74 APP (0.34) CYP1A2CYP2D6
Iodobenzene SCHEMBL4358911 0.73 ALDH1A1 (0.43) ALDH1A1CA2PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5753757-A Electroluminescent polymer compositions and processes thereof XEROX CORPORATION (US) 1998-05-19 US disclosed