Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650721 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2ARAB9ASTAT3STAT1 | |
| SCHEMBL21831291 | 0.76 | TSHR (0.57) | MEN1KMT2ARAB9ASTAT3STAT1 | |
| SCHEMBL23039917 | 0.76 | RAB9A (0.46) | MEN1KMT2ARAB9ASTAT3STAT1 | |
| SCHEMBL8891026 | 0.73 | SMN1; SMN2 (0.48) | MEN1KMT2ARAB9ASTAT3STAT1 | |
| SCHEMBL30518902 | 0.72 | S1PR3 (0.56) | MEN1KMT2ARAB9ASTAT3STAT1 | |
| SCHEMBL8895844 | 0.71 | MEN1 (0.59) | MEN1KMT2ARAB9ASTAT3STAT1 | |
| SCHEMBL28856869 | 0.71 | S1PR3 (0.58) | RAB9ASTAT3STAT1SMYD3S1PR3 | |
| SCHEMBL3092594 | 0.70 | MEN1 (0.52) | MEN1KMT2ASMYD3S1PR3S1PR1 | |
| SCHEMBL8494775 | 0.70 | MEN1 (0.52) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL27626374 | 0.69 | MEN1 (0.51) | MEN1KMT2ARAB9ASMYD3S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625505-B1 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-10-28 | — | — | EP | disclosed |
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |