Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437211 | 0.75 | GRIA1 (0.36) | GRIA1GRIA3GRIA2GRIA4GAA | |
| Aspartic Acid SCHEMBL5964784 | 0.67 | GRIA1 (0.43) | GRIA1GRIA3GRIA2GRIA4MEN1 | |
| SCHEMBL6809086 | 0.67 | CACNA1F (0.33) | — | |
| SCHEMBL8555482 | 0.66 | GRIA1 (0.46) | GRIA1GRIA3GRIA2GRIA4GAA | |
| SCHEMBL13319909 | 0.63 | GRIA1 (0.41) | GRIA1GRIA3GRIA2GRIA4GAA | |
| SCHEMBL5290687 | 0.63 | GRIA1 (0.41) | GRIA1GRIA3GRIA2GRIA4GAA | |
| SCHEMBL4366973 | 0.61 | GRIA1 (0.38) | GRIA1GRIA3GRIA2GRIA4GAA | |
| SCHEMBL68800 | 0.60 | — | — | |
| SCHEMBL11551436 | 0.60 | CNR2 (0.34) | GRIA1GRIA3 | |
| SCHEMBL434029 | 0.58 | HCAR2 (0.52) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830348-A1 | CYCLIC AMINE DERIVATIVES OF SUBSTITUTED QUINOXALINE 2,3-DIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996040650-A1 | CYCLIC AMINE DERIVATIVES OF SUBSTITUTED QUINOXALINE 2,3-DIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |