Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329646 | 0.83 | NPSR1 (0.48) | MTNR1AMTNR1BNPSR1CACNA2D1CACNA1B | |
| SCHEMBL440156 | 0.74 | NPSR1 (0.48) | MTNR1AMTNR1BNPSR1CACNA2D1CACNA1B | |
| SCHEMBL7621551 | 0.74 | MTNR1A (0.49) | MTNR1AMTNR1BNPSR1CACNA2D1CACNA1B | |
| SCHEMBL9342350 | 0.73 | NPC1 (0.37) | NPSR1ALDH1A1HTTKMT2ANPC1 | |
| Water SCHEMBL28256553 | 0.73 | NPSR1 (0.46) | MTNR1AMTNR1BNPSR1CACNA2D1CACNA1B | |
| SCHEMBL28835036 | 0.72 | ALDH1A1 (0.59) | NPSR1CACNA2D1CACNA1BCACNB1ALDH1A1 | |
| SCHEMBL374605 | 0.71 | MTNR1A (0.53) | MTNR1AMTNR1BNPSR1CACNA2D1CACNA1B | |
| SCHEMBL1561383 | 0.71 | NPSR1 (0.44) | MTNR1AMTNR1BNPSR1CACNA2D1CACNA1B | |
| SCHEMBL28104922 | 0.70 | MTNR1A (0.41) | MTNR1AMTNR1BCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL7230081 | 0.70 | ALDH1A1 (0.42) | MTNR1AMTNR1BNPSR1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846130-A4 | NATURAL RUBBER THREAD WITH LOW NITROSATABLE AMINES | ADAM ROGER M (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0846130-A1 | NATURAL RUBBER THREAD WITH LOW NITROSATABLE AMINES | Adam, Roger M. (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5753290-A | VULCANIZED RUBBER LATEX | GLOBE MANUFACTURING CO. (US) | 1998-05-19 | — | — | US | disclosed |
| WO-1997008209-A1 | NATURAL RUBBER THREAD WITH LOW NITROSATABLE AMINES | ADAM ROGER M (US) | 1997-03-06 | — | — | WO | disclosed |