SCHEMBL329646

SCHEMBL329646

O=C(CN(c1ccccc1)c1ccccc1)CN(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.48
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
ALDH1A1 P00352 3/20 0.45
HTT P42858 3/20 0.45
KMT2A Q03164 2/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
GLA P06280 2/20 0.45
POLB P06746 1/20 0.45
TSHR P16473 1/20 0.45
CACNA2D1 P54289 2/20 0.45
CACNA1B Q00975 2/20 0.45
CACNB1 Q02641 2/20 0.45
HDAC1 Q13547 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
KCNH2 Q12809 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440156 0.85 NPSR1 (0.48) NPSR1MTNR1AMTNR1BALDH1A1HTT
SCHEMBL7621551 0.85 MTNR1A (0.49) NPSR1MTNR1AMTNR1BALDH1A1HTT
SCHEMBL8610098 0.83 MTNR1A (0.40) NPSR1MTNR1AMTNR1BALDH1A1HTT
Water SCHEMBL28256553 0.83 NPSR1 (0.46) NPSR1MTNR1AMTNR1BALDH1A1HTT
SCHEMBL374605 0.81 MTNR1A (0.53) NPSR1MTNR1AMTNR1BALDH1A1HTT
SCHEMBL1561383 0.81 NPSR1 (0.44) NPSR1MTNR1AMTNR1BALDH1A1HTT
SCHEMBL28104922 0.80 MTNR1A (0.41) MTNR1AMTNR1BALDH1A1KMT2ANPC1
SCHEMBL3105534 0.79 MTNR1A (0.52) NPSR1MTNR1AMTNR1BALDH1A1HTT
SCHEMBL11754044 0.79 KDM4E (0.54) NPSR1MTNR1AMTNR1BALDH1A1KMT2A
Sulfuric Acid SCHEMBL1626445 0.78 L3MBTL1 (0.43) NPSR1MTNR1AMTNR1BALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 522 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617238-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-05 US disclosed
EP-4722000-A1 TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-04-08 EP disclosed
US-12589615-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-03-31 US disclosed
EP-4706979-A1 TIRE Sumitomo Rubber Industries, Ltd. (JP) 2026-03-11 EP disclosed
EP-4706984-A1 TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-03-11 EP disclosed
EP-4706982-A1 TIRE Sumitomo Rubber Industries, Ltd. (JP) 2026-03-11 EP disclosed
EP-4706983-A1 TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-03-11 EP disclosed
EP-4706987-A1 TIRE Sumitomo Rubber Industries, Ltd. (JP) 2026-03-11 EP disclosed
EP-4703147-A1 TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-03-04 EP disclosed
EP-4703152-A1 TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-03-04 EP disclosed
US-5219942-A Blend of end-modified styrene-butadiene copolymer and diene rubber NIPPON ZEON CO., LTD. (JP) 1993-06-15 US disclosed
US-5217839-A Dispersion containing mixture of a polymer with a carbon nitrogen double bond and a colorant in a vinyl monomer NIPPON ZEON CO., LTD. (JP) 1993-06-08 US disclosed
US-5216080-A Butadiene-styrene copolymers endcapped with N-modified amino ketones, thioamino ketones, thioamino aldehydes, lactams, thiolactams, ethyleneurea and thioethylene urea; wear resistant, large-sized tires NIPPON ZEON CO., LTD. (JP) 1993-06-01 US disclosed
EP-0488346-A1 Process for preparation of styrene resin composition and styrene resin composition NIPPON ZEON CO., LTD. (JP) 1992-06-03 EP disclosed
EP-0438248-A2 Preparation process of toner NIPPON ZEON CO., LTD. (JP) 1991-07-24 EP disclosed
EP-0435544-A2 Abrasion-resistant rubber compositions NIPPON ZEON CO., LTD. (JP) 1991-07-03 EP disclosed
EP-0434353-A2 Rubber compositions NIPPON ZEON CO., LTD. (JP) 1991-06-26 EP disclosed
EP-0388921-A2 Additive for organic solvent or thermoplastic polymer NIPPON ZEON CO., LTD. (JP) 1990-09-26 EP disclosed
US-4950719-A LOW TEMPERATURE VIBRATION INSULATOR NIPPON ZEON CO., LTD. (JP) 1990-08-21 US disclosed
EP-0382205-A2 Additive for thermosetting resins and thermosetting resin composition containing additive NIPPON ZEON CO., LTD. (JP) 1990-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12589615-B2 Pneumatic tire LBR, TERF2, TLN1 NPSR1 4787/4885MTNR1A 3045/4885MTNR1B 3829/4885
US-12617238-B2 Pneumatic tire CCT4, CCT7, CCNE2 NPSR1 4841/4885MTNR1A 3227/4885MTNR1B 3994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.