Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9234601 | 0.98 | MAOA (0.43) | MAOAMAOBTSHRALDH1A1KDM4E | |
| SCHEMBL7282196 | 0.89 | ALDH1A1 (0.42) | MAOAMAOBTSHRALDH1A1KDM4E | |
| SCHEMBL16086532 | 0.84 | TSHR (0.44) | MAOAMAOBTSHRALDH1A1KDM4E | |
| SCHEMBL7899608 | 0.83 | TSHR (0.48) | TSHRALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6535041 | 0.82 | MAOA (0.44) | MAOAMAOBMEN1KMT2ACA12 | |
| SCHEMBL7432213 | 0.82 | TSHR (0.48) | MAOAMAOBTSHRALDH1A1LMNA | |
| SCHEMBL25207862 | 0.81 | TDP1 (0.49) | MAOAMAOBKDM4EMEN1KMT2A | |
| SCHEMBL1566844 | 0.81 | MAOA (0.46) | MAOAMAOBTSHRALDH1A1MEN1 | |
| SCHEMBL9891443 | 0.81 | MAOA (0.46) | MAOAMAOBTSHRRECQLMEN1 | |
| SCHEMBL7429955 | 0.81 | TSHR (0.47) | MAOAMAOBTSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656349-B1 | Amidinophenol derivatives having phospholipase A2 inhibitory activity | ONO PHARMACEUTICAL CO (JP) | 1998-04-08 | — | — | EP | claimed |
| EP-0656349-B1 | Amidinophenol derivatives having phospholipase A2 inhibitory activity | ONO PHARMACEUTICAL CO (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5514713-A | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0656349-A1 | Amidinophenol derivatives having phospholipase A2 inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |