SCHEMBL9891443

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7432213	0.93	TSHR (0.48)	MAOAMAOBEPHX2TDP1TSHR
	SCHEMBL31226873	0.90	EPHX2 (0.44)	MAOAMAOBEPHX2TDP1TSHR
	SCHEMBL2137955	0.89	MAOA (0.44)	MAOAMAOBEPHX2TDP1TSHR
	SCHEMBL693387	0.89	MAOA (0.44)	MAOAMAOBEPHX2TDP1TSHR
	SCHEMBL25525668	0.89	MAOA (0.42)	MAOAMAOBEPHX2TDP1TSHR
	SCHEMBL12581334	0.88	MAOA (0.41)	MAOAMAOBEPHX2TDP1MEN1
	SCHEMBL7428662	0.88	GAA (0.47)	MAOAMAOBEPHX2TDP1TSHR
	SCHEMBL7429955	0.87	TSHR (0.47)	MAOAMAOBEPHX2TDP1TSHR
	SCHEMBL7016949	0.87	RECQL (0.47)	MAOAMAOBEPHX2TDP1TSHR
	SCHEMBL4907521	0.87	MAOA (0.45)	MAOAMAOBEPHX2TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.