Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.61 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.57 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.57 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.57 |
| ▸ | TYMP | P19971 | 8/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.52 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.52 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.52 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.52 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.52 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612194 | 0.91 | ADORA1 (0.54) | ADORA1P2RX3P2RX4P2RX2TYMP | |
| SCHEMBL30592508 | 0.87 | PRKAB2 (0.57) | ADORA1P2RX3P2RX4P2RX2TYMP | |
| SCHEMBL3803391 | 0.86 | TYMP (0.54) | ADORA1P2RX3P2RX4P2RX2TYMP | |
| SCHEMBL13597931 | 0.84 | ALDH1A1 (0.65) | ADORA1P2RX3P2RX4P2RX2PRKAB2 | |
| SCHEMBL10033986 | 0.84 | ALDH1A1 (0.65) | ADORA1P2RX3P2RX4P2RX2PRKAB2 | |
| SCHEMBL23982402 | 0.84 | ALDH1A1 (0.65) | ADORA1P2RX3P2RX4P2RX2PRKAB2 | |
| SCHEMBL8205660 | 0.84 | ALDH1A1 (0.65) | ADORA1P2RX3P2RX4P2RX2PRKAB2 | |
| SCHEMBL4425824 | 0.84 | ALDH1A1 (0.65) | ADORA1P2RX3P2RX4P2RX2PRKAB2 | |
| SCHEMBL11423681 | 0.84 | ALDH1A1 (0.65) | ADORA1P2RX3P2RX4P2RX2PRKAB2 | |
| SCHEMBL19889158 | 0.84 | ALDH1A1 (0.65) | ADORA1P2RX3P2RX4P2RX2PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750675-A | 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosylpurines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | disclosed |
| US-5525720-A | Synthesis of 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosyl purines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1996-06-11 | — | — | US | disclosed |