Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | DHODH | Q02127 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | JAK2 | O60674 | 5/20 | 0.51 |
| ▸ | TYK2 | P29597 | 5/20 | 0.51 |
| ▸ | JAK1 | P23458 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640822 | 0.87 | GRM4 (0.58) | ALDH1A1GAADHODHSMN1; SMN2MEN1 | |
| SCHEMBL18640754 | 0.79 | RAB9A (0.65) | ALDH1A1GAADHODHSMN1; SMN2MEN1 | |
| SCHEMBL1307643 | 0.79 | MEN1 (0.63) | DHODHSMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL3617679 | 0.79 | RAB9A (0.59) | ALDH1A1DHODHSMN1; SMN2MEN1RAB9A | |
| SCHEMBL1307493 | 0.79 | DHODH (0.56) | ALDH1A1DHODHSMN1; SMN2MEN1RAB9A | |
| SCHEMBL3820618 | 0.78 | HTT (0.66) | ALDH1A1GAADHODHSMN1; SMN2MEN1 | |
| SCHEMBL8613320 | 0.78 | DHODH (0.52) | ALDH1A1GAADHODHSMN1; SMN2MEN1 | |
| SCHEMBL8604699 | 0.77 | DHODH (0.64) | ALDH1A1GAADHODHSMN1; SMN2MEN1 | |
| SCHEMBL18640728 | 0.77 | DHODH (0.64) | ALDH1A1GAADHODHSMN1; SMN2MEN1 | |
| SCHEMBL8798613 | 0.77 | DHODH (0.54) | DHODHSMN1; SMN2MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849735-A | Tricyclic benzazepine vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |