Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640822 | 0.82 | GRM4 (0.58) | DHODHKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL8798613 | 0.78 | DHODH (0.54) | DHODHKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL8610236 | 0.78 | ALDH1A1 (0.58) | DHODHKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL18640754 | 0.78 | RAB9A (0.65) | DHODHKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL1307643 | 0.77 | MEN1 (0.63) | DHODHKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL1307493 | 0.77 | DHODH (0.56) | DHODHKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL27474432 | 0.77 | KCNMA1 (0.67) | KMT2AMEN1SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL23796859 | 0.76 | DHODH (0.53) | DHODHKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL7553677 | 0.76 | DHODH (0.56) | DHODHKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL4193561 | 0.75 | DHODH (0.51) | DHODHKMT2AMEN1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849735-A | Tricyclic benzazepine vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |