Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 4/20 | 0.52 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.52 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.52 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.52 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28052253 | 0.71 | — | — | |
| SCHEMBL8869987 | 0.70 | ORAI1 (0.43) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| Phenylboronic Acid SCHEMBL6701482 | 0.70 | ENPP2 (0.74) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| Phenylboronic Acid SCHEMBL28944102 | 0.70 | ENPP2 (0.74) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL4195534 | 0.70 | TRPV6 (0.43) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| Phenylboronic Acid SCHEMBL23824843 | 0.70 | ENPP2 (0.74) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL28972078 | 0.70 | ORAI1 (0.43) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| Diphenyl Borinic Acid SCHEMBL40601 | 0.69 | TRPV6 (1.00) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| Phenylboronic Acid SCHEMBL4453 | 0.69 | — | — | |
| Phenylboronic Acid SCHEMBL8628436 | 0.69 | ENPP2 (1.00) | TRPV6ORAI1ORAI2ORAI3PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022820-A1 | DETECTION OF BIOLOGICAL MOLECULES USING BORONATE-BASED CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | LAWRENCE LIVERMORE NATIONAL LABORATORY (US) | 1998-05-28 | — | — | WO | disclosed |