Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291385 | 0.90 | ALDH1A1 (0.77) | ALDH1A1POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL8611771 | 0.84 | HDAC1 (0.71) | ALDH1A1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL7649688 | 0.83 | HDAC1 (0.49) | ALDH1A1POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL10598594 | 0.82 | POLB (0.66) | ALDH1A1POLB | |
| SCHEMBL1005094 | 0.82 | SOAT2 (0.60) | POLBHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL5695284 | 0.82 | SOAT2 (0.60) | POLBHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL7834597 | 0.82 | SOAT2 (0.60) | POLBHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL1779858 | 0.82 | SOAT2 (0.60) | POLBHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL9776434 | 0.82 | SOAT2 (0.60) | POLBHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL11365418 | 0.82 | SOAT2 (0.60) | POLBHDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998031689-A1 | NOVEL MIXED BENZENE ACID DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 1998-07-23 | — | — | WO | disclosed |