Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610606 | 0.90 | SLC9A1 (0.50) | PTGS2KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL8610875 | 0.88 | CA2 (0.55) | PTGS2GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL8608598 | 0.87 | PTGS2 (0.44) | PTGS2GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL8608047 | 0.85 | PTGS2 (0.52) | PTGS2GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL8608965 | 0.83 | PTGS2 (0.47) | PTGS2GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL8611709 | 0.80 | PTGS2 (0.44) | PTGS2GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL8533240 | 0.80 | SLC9A1 (0.60) | — | |
| SCHEMBL8608333 | 0.78 | CA2 (0.46) | PTGS2KDM4ECA1CA2CA5A | |
| SCHEMBL8607611 | 0.78 | SLC9A1 (0.46) | PTGS2KDM4EALDH1A1MAPT | |
| SCHEMBL8608602 | 0.78 | PTGS2 (0.43) | PTGS2GABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807896-A | Arylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) | 1998-09-15 | — | — | US | disclosed |