Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.50 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 6/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34690 | 0.95 | ALDH1A1 (0.55) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL11371547 | 0.93 | ALDH1A1 (0.46) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL9354769 | 0.88 | ALOX15 (0.68) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL9292312 | 0.88 | ALOX15 (0.68) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL1398405 | 0.86 | ALOX15 (0.47) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL8861305 | 0.85 | ALOX15 (0.44) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL28611519 | 0.82 | ESR1 (0.41) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL19121014 | 0.82 | ALOX15 (0.43) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL19997075 | 0.80 | TSHR (0.41) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL9352375 | 0.80 | ALOX15 (0.42) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780515-A | APPLYING TO PLANTS; REDUCED TOXICITY AND IRRITATION | ROCKHURST UNIVERSITY (US) | 1998-07-14 | — | — | US | claimed |