Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.41 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9352375 | 0.89 | ALOX15 (0.42) | ESR1ALOX15ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL3434639 | 0.89 | ESR1 (0.44) | ESR1ALOX15ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL16237184 | 0.86 | ALOX15 (0.52) | ESR1ALOX15ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL8861305 | 0.85 | ALOX15 (0.44) | ESR1ALOX15ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL19121014 | 0.83 | ALOX15 (0.43) | ESR1ALOX15ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL8611066 | 0.82 | ALOX15 (0.50) | ESR1ALOX15ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL34690 | 0.81 | ALDH1A1 (0.55) | ESR1ALOX15ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL8975143 | 0.81 | LMNA (0.49) | ESR1ALOX15ALDH1A1CYP1A2MAPT | |
| SCHEMBL28612138 | 0.81 | SHBG (0.41) | ESR1ALOX15ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL9252633 | 0.80 | ALDH1A1 (0.41) | ALOX15ALDH1A1KDM4ETP53CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113321626-B | JTP-426467 derivative and synthesis method thereof | 湖南第一师范学院 | 2022-07-22 | — | — | CN | claimed |
| CN-113321627-B | Tafamidis derivative and synthetic method thereof | 湖南第一师范学院 | 2022-05-24 | — | — | CN | claimed |
| CN-113321627-A | Tafamidis derivative and synthetic method thereof | 湖南第一师范学院 | 2021-08-31 | — | — | CN | claimed |
| CN-113321626-A | JTP-426467 derivative and synthesis method thereof | 湖南第一师范学院 | 2021-08-31 | — | — | CN | claimed |
| CN-113321626-B | JTP-426467 derivative and synthesis method thereof | 湖南第一师范学院 | 2022-07-22 | — | — | CN | disclosed |
| CN-113321627-B | Tafamidis derivative and synthetic method thereof | 湖南第一师范学院 | 2022-05-24 | — | — | CN | disclosed |
| CN-113321627-A | Tafamidis derivative and synthetic method thereof | 湖南第一师范学院 | 2021-08-31 | — | — | CN | disclosed |
| CN-113321626-A | JTP-426467 derivative and synthesis method thereof | 湖南第一师范学院 | 2021-08-31 | — | — | CN | disclosed |